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Bio-Bibliography
University of California, Santa Cruz, CA
Sept. 2002
YISHI JIN
Associate Professor of Molecular, Cell, & Developmental Biology
EMPLOYMENT
2000-present Associate Professor of Biology, University of California, Santa Cruz, CA
2000-present Assistant Investigator of Howard Hughes Medical Institute.
1996-2000 Assistant Professor of Biology, University of California, Santa Cruz, CA
1991-95  ostdoctoral Fellow, Massachusetts Institute of Technology, Cambridge, MA
EDUCATION
1991 University of California, Berkeley, Ph.D. (Molecular Biology)
1984 Beijing University, Beijing, P.R. China, B.S. (Biology)
MEMBERSHIPS IN HONORARY SOCIETIES
1999- Society of Developmental Biology (USA)
1996- Society of Neuroscience (USA)
HONORS AWARDS AND GRANTS
2000-05  ackard Award (co-PI)
1996-04 NIH RO1: “GABAergic neuron differentiation in C. elegans”
1999-04 NSF CAREER: “Synaptic remodeling in a simple organism”
1999-01 UC Biotech training grant (co-PI)
1999 NSF Presidential Early Career Award for Scientists and Engineers.
1998-00 UC Biotech training grant (co-PI)
1998 NSF equipment grant (co-PI)
1997-99 Alfred P. Sloan Resarch Fellow
1994-95  ostdoctoral Fellowship from the American Cancer Society
1991-94  ostdoctoral Fellowship from the Jane Coffin Childs Memorial Fund for Medical Research
1993 John Belling Prize in Genetics, Department of Genetics, UC Berkeley,
1985-86  redoctoral Fellowship from the Chinese-United States Biochemistry Examination Association (CUSBEA)
1984 Best Graduate of the Class of 1984, Beijing University
PUBLICATIONS
Hallam. S. J., Goncharov, A., McEwen, J., Baran, R., and Jin, Y. (2002). The C. elegans SYD-1, a presynaptic protein with PDZ, C2 and rhoGAP domains, specifies axon identity. Nature Neuroscience in press.
Huang, X., Huang, P., Robinson, M. K., Stern, M., and Jin, Y. (2002). The metalloprotease and disintegrin protein, UNC-71, regulates axon guidance and sex myoblast migration. Submitted.
Ackley, B.D., Kang, S. H., Crew, J. R., Jin, Y. and Kramer, J. M. (2002). The Basement Membrane Components Nidogen and Type XVIII Collagen Regulate the Organization of Neuromuscular Junctions in C. elegans. submitted.
Huang, X., Cheng, H.-J., Tessier-Lavign, M., and Jin, Y. 2002. MAX-1, a novel PH/Myth4/FERM domain cytoplasmic protein implicated in netrin-mediated axon repulsion. Neuron 34:563-576.
Baren, R., and Jin, Y. (2002) Getting a grip on liprins. Neuron 34:1-2.
Jin, Y. 2002. Synaptogenesis, insights from worm and fly. Current Opinion in Neurobiology. 12:71-79.
Byrd, D. T., Kawasakki, M., Walcoff, M., Hisamoto, N., Matsumoto, K., and Jin, Y. 2001. UNC-16, a JNK signaling scaffold protein, regulates vesicle transport in C. elegans. Neuron. 32: 787-800.
Westmoreland, J. J., McEwen, J., Moore, B. A., Jin, Y., and Condie, B.G. 2001. Conserved function of C. eelgans UNC-30 and mouse Pitx2 in controlling GABAergic neuron differentiation. J. Neurosci. 21:6810-6819.
Crump, J.G., Zhen, M., Jin, Y., and Bargmann, C.I. 2001. The SAD-1 kinase regulates presynaptic vesicle clustering in C. elegans. Neuron 29: 115-129.
Hallam, S., Singer, E., Waring, D., and Jin, Y. 2000. The C. elegans NeuroD homolog cnd-1 functions in multiple aspects of motor neuron fate specification. Development 127: 4239-4252.
Zhen, M., Huang, X., Bamber, B., and Jin, Y. 2000. Regulation of presynaptic terminal organization by C. elegans RPM-1, a putative guanine nucleotide exchanger with a Ring-H2 finger domain. Neuron 26: 331-343.
Chisholm, A.D., and Jin, Y. 2000. Caenorhabditis elegans. in “Encyclopedia of Life Sciences” published on-line by Macmillan Inc.
Zhen, M., and Jin, Y. 1999. The liprin protein SYD-2 regulates the differentiation of presynaptic termini in C. elegans. Nature 401: 371-375.
Eastman, C., Horvitz, H.R., and Jin, Y. 1999 Coordinated transcriptional regulation of the unc-25 glutamic acid decarboxylase and the unc-47 GABA vesicular transporter by the C. elegans UNC-30 homeodomain protein. Journal of Neuroscience 19: 6225-6234.
Jin, Y., Jorgensen, E., Hartweig, E., and Horvitz, H.R. 1999 The C. elegans gene unc-25 encodes glutamic acid decarboxylase and is required for synaptic transmission but not synaptic development. Journal of Neuroscience 19: 539-548.
Jin, Y. 1999. Transformation. “C. elegans, a Practical Approach” ed. I. Hope. Oxford University Press, UK) pp. 69-94.
Hallam, S.J., and Jin, Y. 1998 lin-14 regulates the timing of synaptic remodelling in Caenorhabditis elegans. Nature 395:78-82.
Barnes, T. M., Jin, Y., Horvitz, H. R., Ruvkun, G., and Hekimi, S. 1996. The C. elegans behavioural gene unc-24 encodes a novel bipartite protein similar to both erythrocyte band 7.2 (stomatin) and non-specific lipid transfer protein (nsLTP). Journal of Neurochemistry 67:46-57.
Jorgensen, E.M., Hartwieg, E., Schuske, K., Nonet, M., Jin, Y., and Horvitz, H. R. 1995. Defective recycling of synaptic vesicles in synaptotagmin mutants of C. elegans. Nature 378:196-199.
Belvin, M. P., Jin, Y., and Anderson, K.V. 1995. Cactus protein degradation mediates Drosophila dorsal-ventral signaling. Genes and Development 9:783-793
Jin, Y., Hoskins, R., and Horvitz, H.R., 1994. Control of type-D GABAergic neuron differentiation by C. elegans UNC-30 homeodomian protein. Nature 372:780-783..
Schneider, D.S., Jin, Y., Morisato, D., and Anderson, K.V. 1994. A processed form of the Spatzle protein defines dorsal-ventral polarity in the Drosophila embryo. Development 120:1243-1250.
Chasan, R., Jin, Y., and Anderson, K.V. 1992. Activation of the easter zymogen is required by five other genes to define dorsal-ventral polarity in the Drosophila embryo. Development 115:607-616.
Anderson, K.V., Schneider, D., D. Morisato, Jin Y., and Ferguson E.L. 1992. Extracellular morphogens in Drosophila embryonic Dorsal-ventral patterning. Cold Spring Harbor Symposia on Quantitative Biology LVII:409-417.
Jin, Y., and Anderson, K.V. 1990 . Dominant and recessive alleles of easter are point mutations in the conserved sites in the serine protease catalytic domain. Cell 60:873-881.
Anderson, K.V., Hashimoto, C., Hudson, K., Chasan, R., Jin, Y., and Gerttula, S. 1990. Maternal control of embryonic dorsal-ventral pattern in Drosophila. In The Cellular and Molecular Biology of Pattern Formation, D. L. Stocum and T. L. Karr, eds. (New York: Oxford), pp.31-41.
Gerttula, S., Jin, Y., and Anderson, K.V. 1988. Zygotic expression and activity of the Drosophila Toll gene, a gene required maternally for embryonic dorsal-ventral pattern formation. Genetics 119:123-133.
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