|
Pontine-geniculate-occipital (PGO) wave - A synchronized burst of electrical
activity that originates in the pons and like a wave it activates the lateral
geniculate nucleus (first relay of visual information) and then the occipital
lobe, specifically in the visual cortex (which receives and puts together the
visual information that comes from the lat. geniculate nucleus). PGO waves
appear seconds before and during REM sleep.
The abbreviation "GO" stands for pontine, geniculate, occipital. The term derives from the order of
latency of spike appearance in simultaneous recordings from these areas, with the waves appearing first
in the pons, then propagating to the geniculate and then to the occipital cortex. http://www.npi.ucla.edu/sleepresearch/1183/1183.pdf
The high levels of REM sleep in early life led to the Ontogenetic hypothesis. Within the uterus there is little of the sensory stimulation that the growing cerebrum needs to develop properly. So REM sleep is seen to be a substitute stimulation, which, to a lesser extent is also periodically necessary for the sleeping brain after birth. The key element of REM sleep providing the brain with stimulation seems to be the spike discharges of the pontine-geniculate-occipital (PGO) areas.
|
|