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Ameritec奖成立于1987年,主要表彰对治疗瘫痪有贡献的研究.获奖者将得到40,0000美金的奖励. 自Ameritec设奖以来,时刻于中枢神经再生领域的最新成果保持一致,因此我们可以通过对Ameritec奖奖励的历程来了解脊髓再生的现 Ameritec Prize for Paralysis Research 2005 ~ Dr. Toshihide Yama***a of Chiba, Japan and Dr. Zhigang He of Boston, MA in
recognition of their demonstration that multiple myelin inhibitors of axonal
regeneration mediate their actions by converging on a signaling
pathway involving members of the p75 receptor Family
2003 ~ Dr. Jerry Silver of Cleveland Ohio, USA in recognition of his demonstration
that white matter does not always inhibit axonal extension after CNS injury in adult
mammals and that other factors, especially glycosaminoglycans contribute to the
failure of axonal regeneration.
2002 ~ Dr. Stephen Strittmatter of Connecticut, USA, in recognition of his
accomplishment in molecular isolation of the Nogo-66 receptor, an important
convergent point of action of multiple inhibitors of regeneration.
2001 ~ Dr. Marie T. Filbin of New York USA, and Dr. Mu-Ming Poo of Berkeley,
California, USA, in recognition of their accomplishment in basic research in
demonstrating that stimulation of the cyclic nucleotide signaling pathways can
affect guidance molecules, the growth cone and inhibition of axon regeneration in
the injured spinal cord.
1998 ~ Dr. Thomas M. Jessell of New York, USA, in recognition of his
accomplishment in basic research demonstrating that Sonic Hedgehog (SHH)
and other signaling molecules are critical for inducing the differentiation of
motor neurons, interneurons and other cells in the mammalian spinal cord.
1997 ~ Dr. Corey S. Goodman of Berkeley, California, USA, in recognition of his
accomplishment in basic research through the application of a pioneering
approach, using Drosophila genetics, to identify a large number of molecules,
with equivalence in the human spinal cord that are for axonal pathfinding.
1995 ~ Dr. Marc Tessier-Lavigne of San Francisco, California, USA, in
recognition of his accomplishment in basic research in cloning a type of gene
which guides new nerve growth in the damaged spinal cord.
1993 ~ Dr. Albert J. Aguayo of Montreal, Canada, in recognition of his
accomplishment in basic research demonstrating that nerve cells of the
brain and spinal cord, contrary to then accepted belief, do in fact have the
capacity to regenerate.
1992 ~ Dr. Fred W. Gage of La Jolla, California, USA, in recognition of his
accomplishment in basic research in the promotion of regeneration in the central
nervous system through the use of somatic gene transfer techniques.
1991 ~ Dr. Yves-Alain Barde of Munich, Germany, in recognition of his
accomplishment in basic research in the identification, purification and cloning
of brain derived neurotrophic factor.
1990 ~ Dr. Martin E. Schwab of Zurich, Switzerland, in recognition of his
accomplishment in basic research toward understanding the factors that inhibit
the regrowth of damaged cells in the central nervous system.
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