A post-doctoral position in France fo

>To Students near graduation:

>Ecole Normale Superieure is located in the Latin quarter of Paris, a
>beautiful area to live and work. I have visited ENS biology department,
>which is a first-rate research center in Paris. I just received the
>following announcement from Antoine Triller, who has visited ION last
>year. His work on the assembly of postsynaptic receptors is a very
>impressive piece of work and his experimental approaches are in the
>frontier of cellular neurobiology. I encourage those of you about to
>graduate to consider the postdoc position in his laboratory.




>I can offer a postdoc position for a French or a non-French scientists.
>The position are is starting May-June 2006. A). The position (3 years) is
>a high profile position funded by Inserm (Salary depending on CV).
>
>A post-doctoral positions is available for the study of pre- and
>postsynaptic cell biology using fluorescence technologies. The work of our
>group now focuses on the cell biology and molecular mechanisms of receptor
>accumulation at synapses during development and plasticity. Combining cell
>biology with physical methods, we were able to access high-resolution
>real-time imaging of receptor movements. This structural and dynamic
>approach allows the correlation between molecular diffusion dynamics and
>the organization of the neuronal plasma-membrane not only at steady state
>but also during modifications of the synaptic composition observed during
>synaptic plasticity. We are pursuing this work along two lines of projects
>to understand 1) the molecular basis of synaptic scaling and 2) the
>molecular dynamic at the presynaptic release site.
>
>The project is trans-disciplinary and will be developed at the Ecole
>Normale Supérieure (center of Paris in the Latin quarter), within our
>group being networked with young and gifted investigators from the Physics
>and the Chemistry Department.
>
>Real time imaging including single molecule imaging, FRAP, multiphoton
>imaging and other imaging technologies will be used to study the dynamic
>equilibria within multi-molecular assembly. This approach will be combined
>with cellular and molecular biology methods. Our aim is to unravel in real
>time and in relation with synaptic activity, the interactions between
>transmembrane proteins and scaffolds in the presynaptic release sites and
>in the postsynaptic membrane.
>
>
>Recent publications:
> * Dugue GP, Dumoulin A, Triller A et S Dieudonne (2005) J. Neurosci.
> 25:6490-8.
> * Hanus C, Vannier C et A Triller (2004) J. Neurosci. 24: 1119-1128
> * Dahan M, Lévi S, Rostaing P, Riveau B, et A Triller (2003) .
> Science 302: 442-5.
> * Choquet D et A Triller (2003) Nature Rev. Neurosci 4: 251-265
> * Meier J., Vannier C., Sergé A., A. Triller et D. Choquet (2001
> Nature Neurosci. 4: 253-60.
>Requirements
> * PhD or equivalent in Neuroscience, Cell Biology or Imaging Technolgies
> * All original CVs are welcome
>Applications are invited by e-mail and should include a full CV, a brief
>statement of
>research interests and names/email addresses of 2 references.
>
>Contact
>
>Antoine Triller
><mailto:triller@biologie.ens.fr>triller@biologie.ens.fr
>Biologie Cellulaire de la Synapse
>Inserm U789
>Ecole Normale Supérieure
>46, rue d　Ulm 75005 Paris
>tel: 33 1 44 32 35 47
>fax: 33 1 44 32 36 54