[原创]Anti-Telomere IgG ELISA Kit / 抗端粒抗体ELISA试剂盒

Anti-Telomere IgG ELISA Kit  /  抗端粒抗体ELISA试剂盒

用于Systemic Lupus Erythematosus  (SLE，系统性红斑狼疮) 检测和筛查

Anti-Telomere IgG ELISA for the diagnosis of systemic lupus erythematosus Systemic lupus erythematosus (SLE) is a typical autoimmune disease， which affects almost every organ of the body and  which， with its various symptoms， resembles rheumatic diseases. Although SLE mainly affects women， men and even children can also be affected. Common disorders related to

SLE are malar rash， discoid rash， sensitivity to sunlight， oral ulcers， arthritis， serositis， kidney problems (e.g. proteinuria)， problems related with the central nervous system， blood circulation， the immune system， as well as antinuclear antibodies.The presence of multiple antibodies， especially IgG class antibodies directed against native double-stranded DNA (anti–dsDNA)， is one of the most specifi c tests for SLE. Since the level of circulating antibodies to double-stranded DNA has important diagnostic and therapeutic implications in the treatment of patients with SLE， many techniques have been developed to measure these antibodies.

Telomeres， which represent 0.15 % of the human genome， are highly repetitive sequences of the DNA (TTAGGG/CCCTAA)n at the end of eukaryotic chromosomes. Human antibodies against telomeric DNA is more specifi c and sensitive test for SLE.

The Anti–Telomere IgG antibody test measures by a sensitive and specifi c enzyme immunoassay procedure (ELISA) anti-telomere antibodies in the serum of an SLE patient. Unlike in the conventional DNA antibody tests， which use purifi ed calf thymus DNA as capture antigens for autoantibodies， the newly developed anti–telomere antibody assay is based on the use of double-stranded telomeric DNA as the capture antigen for the binding of antibodies. Anti–telomere antibody assay has several advantages over the conventional anti-dsDNA tests in SLE screening.

604010：Anti-Telomere IgG ELISA Kit， 96 Tests，Kit，参考价：6720元

Anti-Telomere IgG Test 试剂盒优点：

• High affi nity to Anti–Telomere IgG

• Increased specificity (human DNA sequence as a capture antigen)

• Reduced background， no cross-reactions

• High reproducibility

• Easily automated

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