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Title Interaction latency of auditory-visual stimulus onset asynchrony (SOA) in humans Abstract Functions of multisensory cells in brain have been shown to integrate multisensory cues despite quite long temporal displacements between the unimodal stimuli. Unfortunately, nothing is known whether the temporal gap of multisensory SOA can influence on the interaction latency in humans. This study repeated the classic experiment of Giard and Peronnet’s [J. Cogn. Neuroscience 11:5, 473-490], but visual stimulus onset was earlier 15 ms (experiment 1) and 30 ms (experiment 2) than the auditory stimulus onset. We examined the most robust interaction effect which was observed by them in the right fronto-temporal region. The result showed, in both experiments, the latencies of this integrative component are same, as well as this interaction latency is not influenced by the temporal gap. The probable reason is that the multisensory cells in here later receive converging visual input than receive converging auditory input, or receive afferent connections from multisensory association areas, as well as this integrative component is a downstream consequence of this auditory-visual SOA integration.
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