第一牛人王晓东正式任北京生命科学研究所所长

经中华人民共和国科学技术部、北京市人民政府批准，将由王晓东及邓兴旺共同担任首任所长。http://www.cncbd.org.cn/guoji/NIBSvice.htm

王晓东

1 Jiang X, Kim HE, Shu H, Zhao Y, Zhang H, Kofron J, Donnelly J, Burns D, Ng SC, Rosenberg S, Wang X. Related Articles, Links

Distinctive roles of PHAP proteins and prothymosin-alpha in a death regulatory pathway.

Science. 2003 Jan 10;299(5604):223-6.

2 Li LY, Luo X, Wang X. Related Articles, Links

Endonuclease G is an apoptotic DNase when released from mitochondria.

Nature. 2001 Jul 5;412(6842):95-9.

3 Parrish J, Li L, Klotz K, Ledwich D, Wang X, Xue D. Related Articles, Links

Mitochondrial endonuclease G is important for apoptosis in C. elegans.

Nature. 2001 Jul 5;412(6842):90-4.

4Du C, Fang M, Li Y, Li L, Wang X. Related Articles, Links

Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition.

Cell. 2000 Jul 7;102(1):33-42.

5Li K, Li Y, Shelton JM, Richardson JA, Spencer E, Chen ZJ, Wang X, Williams RS. Related Articles, Links

Cytochrome c deficiency causes embryonic lethality and attenuates stress-induced apoptosis.

Cell. 2000 May 12;101(4):389-99.

6Luo X, Budihardjo I, Zou H, Slaughter C, Wang X. Related Articles, Links

Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors.

Cell. 1998 Aug 21;94(4):481-90.





Li P, Nijhawan D, Budihardjo I, Srinivasula SM, Ahmad M, Alnemri ES, Wang X. Related Articles, Links

Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade.

Cell. 1997 Nov 14;91(4):479-89.

PMID: 9390557 [PubMed - indexed for MEDLINE]

Zou H, Henzel WJ, Liu X, Lutschg A, Wang X. Related Articles, Links

Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3.

Cell. 1997 Aug 8;90(3):405-13.

PMID: 9267021 [PubMed - indexed for MEDLINE]

Liu X, Zou H, Slaughter C, Wang X. Related Articles, Links

DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis.

Cell. 1997 Apr 18;89(2):175-84.

Liu X, Kim CN, Yang J, Jemmerson R, Wang X. Related Articles, Links

Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c.

Cell. 1996 Jul 12;86(1):147-57.

邓兴旺

以前投了一些cell，前两年有几篇science和nature，但他还是喜欢自己的老本行---植物，因此plant cell,Trends Plant Sci,Plant J,Plant Physiol等在植物界一流杂志发得很多。这是两年文章

1: Wu P, Ma L, Hou X, Wang M, Wu Y, Liu F, Deng XW.

Phosphate starvation triggers distinct alterations of genome expression in Arabidopsis roots and leaves.

Plant Physiol. 2003 Jul;132(3):1260-71.



2: Peng Z, Shen Y, Feng S, Wang X, Chitteti BN, Vierstra RD, Deng XW.

Evidence for a physical association of the COP9 signalosome, the proteasome, and specific SCF E3 ligases in vivo.

Curr Biol. 2003 Jul 1;13(13):R504-5.



3: Feng S, Ma L, Wang X, Xie D, Dinesh-Kumar SP, Wei N, Deng XW.

The COP9 signalosome interacts physically with SCF COI1 and modulates jasmonate responses.

Plant Cell. 2003 May;15(5):1083-94.



4: Wang X, Feng S, Nakayama N, Crosby WL, Irish V, Deng XW, Wei N.

The COP9 signalosome interacts with SCF UFO and participates in Arabidopsis flower development.

Plant Cell. 2003 May;15(5):1071-82.



5: Wang H, Deng XW.

Dissecting the phytochrome A-dependent signaling network in higher plants.

Trends Plant Sci. 2003 Apr;8(4):172-8.



6: Serino G, Su H, Peng Z, Tsuge T, Wei N, Gu H, Deng XW.

Characterization of the last subunit of the Arabidopsis COP9 signalosome: implications for the overall structure and origin of the complex.

Plant Cell. 2003 Mar;15(3):719-31.



7: Ma L, Zhao H, Deng XW.

Analysis of the mutational effects of the COP/DET/FUS loci on genome expression profiles reveals their overlapping yet not identical roles in regulating Arabidopsis seedling development.

Development. 2003 Mar;130(5):969-81.



8: Wang H, Ma L, Habashi J, Li J, Zhao H, Deng XW.

Analysis of far-red light-regulated genome expression profiles of phytochrome A pathway mutants in Arabidopsis.

Plant J. 2002 Dec;32(5):723-33.



9: Yi C, Wang H, Wei N, Deng XW.

An initial biochemical and cell biological characterization of the mammalian homologue of a central plant developmental switch, COP1.

BMC Cell Biol. 2002 Dec 4;3(1):30. Epub 2002 Dec 04.



10: Schwechheimer C, Serino G, Deng XW.

Multiple ubiquitin ligase-mediated processes require COP9 signalosome and AXR1 function.

Plant Cell. 2002 Oct;14(10):2553-63.



11: Ma L, Gao Y, Qu L, Chen Z, Li J, Zhao H, Deng XW.

Genomic evidence for COP1 as a repressor of light-regulated gene expression and development in Arabidopsis.

Plant Cell. 2002 Oct;14(10):2383-98.



12: Hou Y, Von Arnim AG, Deng XW.

A New Class of Arabidopsis Constitutive Photomorphogenic Genes Involved in Regulating Cotyledon Development.

Plant Cell. 1993 Mar;5(3):329-339.



13: Fry RC, Habashi J, Okamoto H, Deng XW.

Characterization of a strong dominant phytochrome A mutation unique to phytochrome A signal propagation.

Plant Physiol. 2002 Sep;130(1):457-65.



14: Yadav V, Kundu S, Chattopadhyay D, Negi P, Wei N, Deng XW, Chattopadhyay S.

Light regulated modulation of Z-box containing promoters by photoreceptors and downstream regulatory components, COP1 and HY5, in Arabidopsis.

Plant J. 2002 Sep;31(6):741-53.



15: Liu Y, Schiff M, Serino G, Deng XW, Dinesh-Kumar SP.

Role of SCF ubiquitin-ligase and the COP9 signalosome in the N gene-mediated resistance response to Tobacco mosaic virus.

Plant Cell. 2002 Jul;14(7):1483-96.



16: Hardtke CS, Okamoto H, Stoop-Myer C, Deng XW.

Biochemical evidence for ubiquitin ligase activity of the Arabidopsis COP1 interacting protein 8 (CIP8).

Plant J. 2002 May;30(4):385-94.



17: Holm M, Ma LG, Qu LJ, Deng XW.

Two interacting bZIP proteins are direct targets of COP1-mediated control of light-dependent gene expression in Arabidopsis.

Genes Dev. 2002 May 15;16(10):1247-59.



18: Wang H, Deng XW.

Arabidopsis FHY3 defines a key phytochrome A signaling component directly interacting with its homologous partner FAR1.

EMBO J. 2002 Mar 15;21(6):1339-49.



19: Suzuki G, Yanagawa Y, Kwok SF, Matsui M, Deng XW.

Arabidopsis COP10 is a ubiquitin-conjugating enzyme variant that acts together with COP1 and the COP9 signalosome in repressing photomorphogenesis.

Genes Dev. 2002 Mar 1;16(5):554-9.