视听觉综合的理论基础

下面是我将在今年8月份在美国Boston发的论文中的INTRODUCTION中的一部分

解剖学方面：
Neurons that respond to stimulation in more than one modality have been identified in the deep layers of the superior colliculus of a number of species. Each bi- or trisensory neuron in this structure contains a map of sensory space, one for each sense (visual, auditory, tactile) to which it responds. The different maps overlap each other so that stimuli from different sensory modalities originating in the same spatial location activate the same region of the superior colliculus. [Cereb. Cortex. 11(12):1110-1123].Similar multisensory integrations have also been shown to operate at the cortical level [Exp. Brain Res. 91: 484-488].
行为学方面：
bimodal target stimuli were responded to much faster and were identified more accurately than the unimodal target stimuli.
功能成像方面：
To investigate the neural basis of such crossmodal interaction, event-related potential (ERP) to the ‘auditory alone’ (A) and ‘visual alone’ (V) stimulus conditions were summed (A+V) and compared to the ERP to the simultaneously presented auditory and visual stimuli (AV). If neural responses to the auditory and visual inputs were processed in the same way when they were presented simultaneously as when they were presented alone, then, based on the principle of superposition of electrical fields, AV would be equivalent to A+V. However, if the neural responses to the simultaneously presented auditory and visual stimuli interacted during processing, the AV and A+V would diverge (i.e. interaction = AV – (A+V)). This method of measuring multisensory processing is valid when neural responses reflect sensory processing unique to the stimulus, and do not reflect processes common to all three stimulus types such as target (e.g. the P3) or response (e.g. motor cortex activity) related neural activity [Cogn. Brain Res.14(1):115-128].

那你的初步结果是什么呢？
A+V<AV??
是的话，这种interaction会是发生在什么部位以及什么时候发生的呢和咋样发生的呢？where，when and how？？

过去的方法是比较av与a+v，无论av>a+v还是av<a+v都属于发生综合
where：最早的av成分在v1，潜伏期约40ms。联合皮质比较多，听皮质也有。详细的内容参看我给你的3篇论文

好的，我还没有仔细看，
看过后，再说说，呵呵

atlantis
能说的再详细些吗?

Maybe you should pay attention on Dr. Wolf Singer&#39;s research on r-oscillation (40Hz Oscillation).