[转贴]Visual memory

Visual memory task for rats reveals an essential role for hippocampus and perirhinal cortex

G. T. Prusky * , R. M. Douglas * , L. Nelson *, A. Shabanpoor * and R. J. Sutherland *

*Canadian Centre for Behavioural Neuroscience, University of Lethbridge, 4401 University Drive, Lethbridge, AB, Canada T1K 3M4; and Department of Ophthalmology and Visual Sciences, University of British Columbia, 2550 Willow Street, Vancouver, BC, Canada V5Z 3N9

Edited by Larry R. Squire, Veterans Affairs Medical Center, San Diego, CA, and approved February 18, 2004 (received for review December 31, 2003)


Visual recognition memory is subserved by a distributed set of neural circuits, which include structures of the temporal lobe. Conflicting experimental results regarding the role of the hippocampus in nonspatial forms of such memories have been attributed to species, task, and lesion discrepancies. We have overcome obstacles that have prevented a direct evaluation of the role of the hippocampus in this type of memory by developing for rats a nonspatial, picture-based, trial-unique, delayed matching-to-sample task that is a procedural analogue of standard visual recognition memory tasks used in primates. With this task, we demonstrate that rats have a visual memory profile, which is analogous to that in primates and depends on the function of perirhinal cortex. We also find that selective lesions of hippocampus impair delay-dependent visual memory with a profile different from that produced by damage to the perirhinal cortex. These data demonstrate that rats have a visual recognition memory system fundamentally similar to primates that depends on the function of the hippocampus.

收到，thanks

Abstract
The perirhinal cortex plays a key role in acquiring knowledge about objects. It contributes to at least four cognitive functions, and recent findings provide new insights into how the perirhinal cortex contributes to each: first, it contributes to recognition memory in an automatic fashion; second, it probably contributes to perception as well as memory; third, it helps identify objects by associating together the different sensory features of an object; and fourth, it associates objects with other objects and with abstractions.

怎样能看到 Current Opinion in Neurobiology 的全文？如果有密码，发个给我好吗？
remind_me@163.com

这段话有什么特别的，不明白。老鼠和猴子记忆系统相似？是很重用的发现吗？（我是业余的）

很多时候，老外的思想，在我们看来却是很奇怪
老鼠是rodent类，（ 哺乳纲中种类最多、分布最广的一类动物。没有犬齿,门齿与前臼齿间有空隙。以食植物为主。大多数种类繁殖迅速,如兔类和鼠类动物）
猴是高等灵长类，
进化上是有意义的

是否可以这么理解：以往人们认为差别应该很大，而这篇论文说明没这么大，视觉记忆系统很相似。

如果是这样，那么其他记忆系统呢？目前已知rats和primates差别是否很大？

呵呵，小声提醒一下下，你好像没有看清上面摘要的意思哦！！！

呵呵，重点是标题，而我把不重要的部分当成重用的，是不是啊？

有问题多批评。

请问，perirhinal 是什么意思，字典上查不到。另外，海马和这个皮层，对于视觉记忆的重要性是否以前不清楚？

perirhinal的中文是"鼻周的”
有兴趣，你可以去看看
Role of perirhinal cortex in object perception, memory,and associations
Elisabeth A Murray* and Barry J Richmond
Current Opinion in Neurobiology 2001, 11:188–193

The same request with remind_me.
alexjyu2@yahoo.com.cn